Ernani. A Tragic Opera, in Four Acts

To Seek the Holy Grail of Cardiac Progenitor Cells: An Opera in Four Acts.

Discoveries in cardiovascular stem cell biology, myocyte regeneration, and cell transplantation have enormous clinical potentials, yet the field is embroiled in amusing controversies. The existence of cardiac myocyte progenitor cells (CPCs) in the adult heart, let alone the identity of the genuine CPCs, has been debated and so has the relevance of the primary candidate, namely the resident card...

Hysteria in Four Acts

I 1973, the journalist Flora Rhea Schreiber collaborated with Cornelia Wilbur, a Manhattan psychiatrist, in writing Sybil., the story of a young woman who, while under Wilbur's care, developed sixteen "personalities." In each distinct "alter"— alternative personality—she behaved in a different way, at one time or another "depicting" aggressive males, defenseless children, and intellectual women...

The peroxisome: a production in four acts

A cell regulates the number, size, and kind of each organelle it possesses in response to its particular role in an environment or tissue. Yet we still know little about how the molecular signaling networks within each cell perform such regulation. In this issue, Saleem et al. (Saleem, R.A., B. Knoblach, F.D. Mast, J.J. Smith, J. Boyle, C.M. Dobson, R. Long-O'Donnell, R.A. Rachubinski, and J.D....

A Tragic Loss

T he circumpolar health community lost a much respected and loved friend, colleague and mentor on 17 June, 2014. Dr. Éric Dewailly, aged 59, a professor at Laval University in Québec, Canada, died in a tragic rockslide on the island of Réunion in the Indian Ocean, while holidaying with his family. Eric was well known to many researchers across the Arctic. He was a superb pioneering scientist wh...

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